COUROUPITA SP. ENHANCED SILVER NANOPARTICLES AS POTENT ANTICANCER AGENT

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Published Oct 30, 2018
DOI https://doi.org/10.5281/ijrset.v3i12.235

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Kavipriya .
Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore- 641 046
Balaji K.S.
Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore- 641 046
Vinayaga Moorthi P
Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore- 641 046
Selvarani S
Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore- 641 046
Puthamohan Vinayaga Moorthi
Assistant Professor, Department of Human Genetics and Molecular Biology, Department of Zoology, Thiagarajar College, Madurai-625009

Abstract

Couroupita sp. flower extract enriched silver nanoparticle was synthesized in the present investigation. It was characterized by its excitation at 428nm which was observed in UV-Vis spectrophotometer. Their spherical shaped presence was been clearly noticed in SEM image. In the FT-IR spectrum intense peaks were observed for silver nanoparticles at 975.93, 1637.48 and 3348.25 cm−1 . The cytotoxic assay of silver nanoparticles against MCF-7, the breast cancer cell line revealed excellent anticancer potential of the nanoparticle and the IC50value was 164.69µg/mL. Thus, it reveals the anticancer potential of AgNps enriched with flower extract which will be further studied for its cancer therapy.

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Issue
Vol 3 No 12 (2016): Volume 3 Issue 12
Section
Articles